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Active ingredient: Benazepril

ACE inhibitor. After hydrolysis, Benazepril is converted to an active metabolite, benazeprilate, which inhibits ACE and thereby blocks the conversion of angiotensin I to angiotensin II and reduces the vasoconstrictive effect of angiotensin II and its stimulating effect on aldosterone production. Due to the venodilating effect, it also reduces the preload on the heart. Effective for arterial hypertension, CHF (as part of combination therapy)

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Lotensin Product Description


Drug Uses

The antihypertensive agent Lotensin is used for the treatment of people, who are really suffering from high blood pressure. Typically, Lotensin pills are used to treat mild to moderate hypertension, but if necessary, may provide substantial benefits in severe type of the disease.

Response to hypertension treatment with Lotensin pills implies long control of blood pressure and reduced risk of heart attack and stroke. For stabilizing the blood pressure, 20 to 40 mg of Lotensin should be taken per day in single or multiple doses.

The minimum dosage is 10mg Lotensin at intervals of 24 hours. The antihypertensive drug is prescribed to children older than 6 years based on their body weight (0,2-0,6mg/kg). The adults should take no more than 2 Lotensin pills 40mg per day.


Missed Dose

If you forget to take a dose of Lotensin, take it as soon as possible. Do not use a double dose of this antihypertensive agent in a case if there is almost time of your next prescribed dose.


More Information

The effectiveness of the antihypertensive therapy may increase, if you use Lotensin pills with diuretics. The minimum Lotensin dosage in the combined treatment of high blood pressure is 5 mg per day.


Storage

Keep Lotensin in an original tightly closed container at room temperature below 30°C. Lotensin tablets must be protected from heat, light and moisture.


Lotensin Safety Information


Warnings

Women of childbearing age, with regular sex activity, should use reliable contraceptives, when taking Lotensin. If the pregnancy test was positive, you must immediately stop taking the antihypertensive agent Lotensin.


Disclaimer

The information about the management of hypertension and high blood pressure, provided in this review study on Lotensin, is for informational purposes only and does not serve as a substitute for personal advice from a licensed occupational physician. The online pharmacy is not liable for any kind of damage or loss, resulting from the misinterpreting and misusing of this material about antihypertensive agent Lotensin.


Lotensin Side Effects


All the undesirable effects, which manifest during treatment with Lotensin, have a soft flowing nature and are not conditioned by the age and sex of the patient, as well as the duration of treatment and dosage of this antihypertensive agent. A total of about 5% of withdrawals of Lotensin use was registered because of the undesirable effects. The patients taking Lotensin pills, most often complain of such undesirable effects, like cough, dizziness, headache and somnolence.

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The drug is an inhibitor of the enzyme peptidyl. It inhibits the angiotensin-converting enzyme, which catalyzes the conversion of angiotensin I to vasoconstrictor peptide angiotensin II. Angiotensin II also stimulates the secretion of aldosterone by the adrenal cortex. Inhibition of ACE leads to reduced concentrations of angiotensin II, resulting in low aldosterone secretion. The decrease in the latter leads to an increase in the content of potassium in the blood serum. Since the mechanism is believed to be based on the inhibition of the renin-angiotensin-aldosterone system, it reduces blood pressure even in patients with hypertension with low renin levels.

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