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Gastrointestinal
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Active ingredient: Domperidone

stimulant of the intestinal peristalsis. Motillium is assigned in cases of: distention, overeating, vomiting, heartburn, flatulence, a feeling of overflow of the stomach.

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Product Description


Motilium - a stimulant of intestinal peristalsis, also has an antiemetic effect.The active substance is domperidone.Possessing the effects of some neuroleptics and metoclopramide, domperidone is a dopamine antagonist.


Safety in formation


Indications and usage

dyspeptic phenomena that are associated with gastro-esophageal reflux, delayed gastric emptying, esophagitis;
nausea and vomiting associated with the reception of dopamine agonists in Parkinson's disease;
nausea and vomiting, infection, organic or functional nature, as well as nausea and vomiting associated with diet disorder, radiotherapy or drug treatment;
Cyclic vomiting, regurgitation syndrome, gastro-oesophageal reflux disease and other changes in gastric motility in children.


Mode of application

Intakefor 15-30 minutes before meals and at bedtime (if necessary).

In chronic dyspeptic conditionsin adults and children over 12 years - 10 mg (1 tablet) 3 times daily.In the absence of the desired effect, the indicated dosage for adults and children over 12 years can be doubled.The maximum daily dose is 80 mg.

Children from 5 to 12 years- 10 mg (1 tablet) 3 times a day.The maximum daily dose is 2.4 mg / kg, but not more than 80 mg.

If nausea and vomitingin adults and children over 12 years - 20 mg (2 tablets) 3-4 times a day (maximum daily dose - 80 mg);Children 5-12 years - 10 mg (1 tablet) 3-4 times a day.The maximum daily dose is 2.4 mg/kg, but not more than 80 mg.

Tablets for Motiliumis only shown for adults and children weighing more than 35 kg in pediatric practice is mainly to use Motilium suspension.With renal failure, a reduction in the frequency of taking the drug is recommended.


Contraindications

gastrointestinal perforation or obstruction mechanical etiology;
prolactinoma;
gastrointestinal bleeding;
hypersensitivity to domperidone Motilium or other components;
reception on the background of ketoconazole in oral forms of release.


Side effects


On the part of the endocrine system: amenorrhea, gynecomastia, it is possible hyperprolactinemia, which occasionally leads to galactorrhea.
From the side of the central nervous system: very rarely possible extrapyramidal disorders in children.They are reversible and stop when the medicine is discontinued.In adults, extrapyramidal disorders are extremely rare.In children under 1 year due to insufficiency of the blood-brain barrier or in violation of its functions, side effects of a neurological nature are possible.

On the part of the digestive system: digestive disorders (rare), in rare cases, transient spastic contractions of the intestine are possible.
Allergic reactions: urticaria and rash (rarely).

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