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Antibiotics
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Active ingredient: trimethoprim sulfamethoxazole

Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.

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Bactrim Product Description


Drug Uses

Bactrim is a synthetic antibacterial combination product to block the metabolism in cells of pathogenic microorganisms. It provides broad-spectrum antibacterial activity against infections caused by Gram-positive and Gram-negative pathogens.

Antimicrobial Bactrim is prescribed for children (aged 2 month old and above) and for adult patients for the treatment of:

middle ear infection

wound and skin infections

urogenital system infections

gastrointestinal tract infections

upper and lower respiratory tract infections

Bactrim dose is titrated individually, taking into account the disease severity and the microorganisms’ sensitivity to antibiotics. In acute infections, the patients are indicated to take Bactrim for 5-7 days. Children over 12 and adults are prescribed to take one Bactrim DS (double strength) tablet in the morning and evening after meals.

A pediatric dose of Bactrim is titrated for children under 12 years of age, considering the child’s body weight and age. Elderly patients with normal renal function are usually indicated with the regular dose for adults.


Missed dose

If you have missed a pill of antibacterial drug Bactrim, take it as soon as you remember and keep complying with the regular dosing schedule. Do not take the missed dose of Bactrim, if it is time for the next dose of synthetic antimicrobial drug. The drug should be taken according to the dosing schedule, do not take extra medicine to make up the missed dose of Bactrim.


More Information

Bactrim should be indicated with caution in patients with asthma and prone to allergic reactions. During antimicrobial treatment with Bactrim, the patients are advised to drink plenty of water and have urine output in order to reduce the possibility of crystalluria.

Bactrim pills are recommended to take whole, after a meal with a full glass of water. To ensure the antibiotic therapy efficiency, the patient should comply with the prescribed dosage regimen and not withdraw Bactrim use at the first signs of the state improvement. Premature withdrawal of the antibiotic therapy may cause the infection relapse.


Storage

Bactrim can be stored for 5 years if kept in the outer carton at temperature not above 25°C. It is recommended to protect antibiotic Bactrim from light.


Bactrim Safety Information


Warnings

Bactrim is advised to be prescribed with extreme caution to elderly patients taking diuretics (particularly, thiazides), because it increases the risk of Werlhof's disease (autoimmune thrombocytopenic purpura).

Clinical studies have verified that Bactrim may change an anticoagulant effect of anticoagulants. Therefore, in case of coadministration of antibacterial drug Bactrim with acenocoumarol or warfarin, activated clotting time is recommended to be adjusted again. It should be mentioned that Bactrim may decrease the effectiveness of tricyclic antidepressants, and weaken the contraceptive effect of birth control pills.

Coadministration of Bactrim with immunosuppressive medications (i.e. mercaptopurine, cyclosporine and azathioprine) may result in blood disorders. Bactrim is to be indicated with caution to patients taking antiviral medications. This combination of drugs increases the risk of acute confusional state and muscle twitching (myoclonus).


Disclaimer

This information on the Bactrim is provided for general informational purposes only and shall not be used as recommendations how to treat bacterial infections if such treatment was not indicated by your doctor.

The online pharmacy shall not be liable for any incidental, indirect, or consequential damage which may arise through the access to information about Bactrim and from the combination antibiotic therapy.


Bactrim Side Effects


Therapeutic action of Bactrim may be accompanied with such undesirable effects as hyperkalemia, headache and candidiasis. Sometimes undesirable effects involve the gastrointestinal system and cause vomiting, appetite loss, diarrhea, or nausea. In addition, different allergic skin reactions can be observed during the treatment with Bactrim.

Most common of allergic undesirable effects include urticaria and rash. Overdose of antibiotic Bactrim may cause such undesirable effect as high serum potassium concentration in the body. Very rarely, Bactrim is reported to cause hypersensitivity. If a severe form of this undesirable effect is met, Bactrim intake should be immediately stopped.

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