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Anti-Depressant
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Active ingredient: Nortriptyline

Pamelor is a tricyclic antidepressant (TCA, tricyclic antidepressants) of the second generation. It is used in the treatment of some major depressive disorder and nocturnal enuresis (bedwetting) in children. In addition, the drug is sometimes used for the treatment of chronic diseases such as chronic fatigue syndrome, chronic pain and migraine, and the lability in certain neurological diseases.

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Pamelor Product Description


Drug Uses

Pamelor is a tricyclic antidepressant used to treat major depressive disorder. Also, this antidepressant can be administered for a long-term supportive treatment of recurrent depression. Clinical trials have demonstrated that the antidepressant inhibits the catecholamines activity and is characterized by a combination of stimulant and depressant properties.

A good safety and tolerability profile allows to use tricyclic antidepressant Pamelor for the treatment of major depression not only in adults and elderly patients, but also in adolescents aged 12 years and over.

The antidepressant therapy is recommended to be started with a low dose of Pamelor. A usual adult dose Pamelor makes from 75 to 100 mg per day, separated by 3 to 4 intakes. The maximum adult dose of the antidepressant is 150mg per day. For the treatment of depressive disorders in adolescents and elderly patients, the recommended dose of Pamelor is 30 to 50 mg per day.


Missed dose

If you’ve missed one dose of Pamelor, do not worry, and take the antidepressant as soon as you remember. Do not take the missed dose of Pamelor, if it is time for the next dose of the tricyclic antidepressant. Do not take additional antidepressants or double doses of Pamelor to make up the missed dose.


More Information

Pamelor is characterized by the property to prevent nocturnal diuresis in childhood. But the drug is not approved for the treatment of urological problems in children, so it can be used for prophylaxis of nocturnal enuresis only as "off-label".


Storage

Pamelor tablets should be stored at temperature between 20° and 25°C in a dry warm place, away from children, in their original package.


Pamelor Safety Information


Warnings

Pamelor may worsen depression symptoms and suicidal thoughts development in some patients suffering from major depressive disorder. If during the antidepressant therapy with Pamelor the patient experiences such symptoms as hostility, panic attacks, aggressiveness, hypomania, anxiety, the dosage regimen of Pamelor should be changed. If depression symptoms are worsening all the same in spite of taken measures, the application of antidepressant Pamelor should be ceased and some alternative treatments for depression should be considered.


Disclaimer

This information on Pamelor is provided for general informational purposes only, and shall not be used as recommendation how to treat symptoms of depression, if such treatment was not indicated by your doctor. The online pharmacy shall not be responsible for any claim of loss or damages suffered by any person, for any decisions, whether taken or not, based on subjective interpretation of information about antidepressant Pamelor.


Pamelor Side Effects


Unwanted effects of Pamelor are reported to be mild to moderate and generally reversible. Most often the antidepressant causes: low blood pressure, high blood pressure, confusional states, numbness, tingling, dry mouth, skin rash, petechiae, bone marrow depression, nausea, vomiting, anorexia, and icterus. Less commonly, the patients taking Pamelor may complain of: tachyarrhythmia, palpitation, disorientation, delusions, anxiety, ataxia, tremors, gingivitis, agranulosis, eosinophilia; purpura, epigastric distress, diarrhoea, increased or decreased libido or impotence.

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