Combivir - the antiviral combined medicine. Lamivudin and zidovudine are highly effective selective inhibitors of HIV-1 and HIV-2. Lamivudin is a synergist of a zidovudine concerning oppression of replication of HIV.
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Combivir product description
Combivir is an antiviral drug for the therapy of HIV infection in adults and children weighing at least 14 kg. Many doctors around the world successfully use it in practice since it shows good effectiveness. The main ingredient of medicine is lamivudine.
Combivir safety information
The drug is contraindicated in people who respond poorly to lamivudine and zidovudine (the main components of the drug).
Also, Combivir is not allowed to take for people with low hemoglobin and leukocyte counts.
To ensure the accuracy of dosing, the pills must be swallowed at one time. Those persons who have difficulty in swallowing, have to crush the remedy and add them to a small amount of semi-solid food or liquid. All the amount of the mixture should be taken immediately.
The medicine must be taken in the period of pregnancy in case only if the health benefits of the mother exceed the health benefits of the child. Combivir seeps into breast milk, so it will be necessary to refuse to breastfeed, as this may lead to complications for the child's health.
There is no specific information on the use of Combivir in old persons. Nonetheless, special care must be taken, in the care of elderly persons. Therapists have to take into account age-related changes, for example, contrasts in hematologic indices and impaired renal function.
Symptoms: information about cases of overdose of Combivir is limited. No specific symptoms were detected in acute overdose except those that are related to the side condition of the medication. No one of these occasions ended in a fatal outcome, and the condition of all people returned to normal life.
Therapy for overdose: if the person has exceeded the needed part of the medicine and got side things, it is recommended to monitor his self-condition for the timely detection of signs of intoxication and to conduct standard maintenance therapy.
Combivir - side effects
As for the side occasions of the drug, they are quite a large number and it all depends on the individual patient who takes the drug.
Speaking generally, the drug can affect the blood condition and even cause anemia. Also, the side situations of taking Combivir may cause difficulties with metabolic processes in the organism, such as weight gain, anorexia, or lactic acidosis. As for the gastrointestinal tract it can cause nausea, vomiting, diarrhea and pancreatitis. In such cases, you need to revise the course of taking medicine, perhaps to cancel it.
As for the nervous system, there are some situations, when people started a feel headache. After taking high doses of the drug may increase the level of liver enzymes.
All adverse events were observed, mainly in patients who exceeded the drug's dosage.
More details about what side situation may occur in your own case you will understand after consulting a doctor. Be sure to tell the specialist about what therapy you are taking in parallel (if you are going through) and tell us about the presence of any diseases that can become a barrier to the drug being prescribed for you.