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Gastrointestinal
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Aciphex

Active ingredient: Rabeprazole

Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.

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Aciphex Product Description


Drug Uses

Aciphex exerts an anti-secretory action on parietal (oxyntic) cells of the stomach, reduces the amount of gastric juice, inhibits the hydrochloric acid production, promotes a high degree of mucosa defects healing, and is used:

  • For monotherapy of ulcers of various intestine parts, as well as for the prevention of recurrent relapses.
  • In combination with antimicrobial agents for the eradication of spiral-shaped micro-organisms in the mucous layer of the stomach (H pylori).

Doctors recommend taking one Aciphex 20mg pill per day for a period of 30 to 60 days for restoring the bowel function. A second course of the treatment may be required for a complete healing.

The daily Aciphex dosage can be increased to 60 mg every 12 hours, if the excessively high concentration of the hormone gastrin provoked a severe intestinal damage (e.g., Zollinger-Ellison syndrome).


Missed Dose

If the patient is taking Aciphex tablets in the morning, he/she can take the missed dose throughout the day. The dose should be omitted, if it is too close to the time for the next dose. Simultaneous intake of two doses does not increase the treatment efficacy.


More Information

Aciphex reduces the amount and activity of gastric juice, which can affect the absorption of B group vitamins. The patients are recommended to take supplementary multivitamins in case of medium-term or long-term treatment with acid-reducing pills Aciphex.


Storage

To protect Aciphex tablets from moisture, they should be kept in a tightly closed container, at room temperature up to 25°C.


Aciphex Safety Information


Warnings

Regular endoscopic examinations may be recommended to patients, taking Aciphex, especially in prolonged or repeated treatment with this acid-reducing drug. Such preventive measures are connected with the ability of Aciphex to hide the first signs of gastrointestinal tract cancers and other serious diseases. Aciphex contains inactive ingredients that hinder the rapid penetration of the entire dose into the bloodstream. You should not crush Aciphex tablets, even if you need to use half a dose.


Disclaimer

This Aciphex review contains only general information about medical conditions and treatments of gastrointestinal diseases. Any information provided about Aciphex should not be used to replace the advice of the gastroenterologist or other licensed medical practitioner. The online pharmacy shall not be liable for any loss or damage of whatever nature (direct, indirect, consequential or other), relating to or arising from the use of information provided about the acid-dependent diseases and Aciphex.


Aciphex Side Effects


Aciphex is usually well tolerated, and the side effects appear only at the initial stage of its use. A small percentage of adults, using this proton pump inhibitor for a short-term therapy, may get pharyngitis, flatulence, infection and constipation.

Adolescents, using Aciphex for a long-term treatment, may have abdominal pain, nausea, vomiting, diarrhea and headache. It is noteworthy that the side effects, possible in children and adolescents, are rarely observed in adult patients.

Postmarketing experience showed that patients taking Aciphex may feel disorientation and delirium, drug eruptions of the skin and jaundice. Less commonly, patients complain of gynecomastia, skin eruption, toxic epidermal necrolysis, and bone fractures. The incidence of these side effects is unknown.

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