Duphaston - gestagenic medicine, makes the selection impact on endometria, promotes formation of a normal secretory endometria at women after preliminary therapy by estrogen. It is taken at the infertility caused by luteal deficiency. It is also effective at treatment of gestagenny insufficiency, endometriosis; secondary amenorrheas; dysfunctional metrorrhagia; premenstrual syndrome.
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Duphaston product description
Artificially created the most important female hormone - Duphaston, very delicately, without damaging the female health, impacts the reproductive function. The drug provides such a desirable pregnancy and also contributes to keeping it. Inflammatory processes, tumors or other ovarian damage, in which progesterone is produced, disrupt hormone production and reduce reproductive function. To replenish progesterone in the body of a female, hormone treatment with a drug such as Duphaston, as well as various analogs, is necessary.
To start a course of Duphaston therapy, you do not need to take tests to confirm the lack of progesterone in the body, since most often this shortcoming is obvious. The most frequent cause for a prescription for the drug consumption is the risk of miscarriage (plus bleeding during the first weeks of pregnancy, endometriosis, as well as dishormonal uterine bleeding). According to doctors, Duphaston actively influences infertility, it also facilitates painful menstruation and painful PMS. In addition, this medication has an excellent effect on amenorrhea (the absence menstruation), dysmenorrhea, and is an excellent support for successful implantation (fixedness of a fecundated egg to the wall of the uterus) and fetal advancement. Duphaston is also assigned for insufficiency of the luteal phase, as well as for surgical castration.
Duphaston safety information
Usually, Duphaston tablets are prescribed several times a day at a dosage of 10mg to 40mg. The exact dosage and the regimen is determined by the healthcare provider, based on the data of the particular patient and her illness. The pharmaceutical Duphaston is prohibited when the patient has: liver disease as a syndrome of the rotor (hereditary liver disease is characterized by impaired metabolism in hepatocytes, liver cells, and the appearance of dystrophic changes); and also with Dabin-Johnson syndrome (chronic benign disease, characterized by unstable jaundice).
This medical agent is allowed for the use by a pregnant woman, but when using a medicament during lactation, the feeding should be canceled, as the pharmaceutical penetrates into the breast milk and that can harm the child.
Duphaston side effects
Duphaston is a medical preparation used in the therapy of various diseases caused by a deficiency of progestogen in the body of the female. The basic substance of this medication - dydrogesterone, a progestogen analog, actively affects some progestin receptors of the uterus. However, there are no adverse reactions of Duphaston analogs, which are synthetic progestins. The use of Duphaston allows normalizing the progestogen without affecting either ovulation, metabolism, or other processes in the body. In addition, the description of Duphaston suggests that the remedy also has no negative influence on the baby (in case the tablets were taken by a woman during pregnancy).
However, it is extremely rare when using this pharmaceutical, such a side effect as bleeding may occur. In this case, the amount of dydrogesterone taken is increased. Also, there is a likelihood of an individual hypersensitivity to the medication.